Over the past year, the topic of research misconduct has become a headline in popular news media and given rise to new, and renewed, interest in the authenticity of data from both regulators as well as the general public. In particular, in the past year, we have seen a heightened scrutiny of potential plagiarism and unprofessionalism in scholarly works as well as intensified scrutiny on the potential for erroneous data to impact entire portfolios and even impact entire scientific disciplines. In this session, we will discuss new trends in allegations of research misconduct proceedings — from the manner in which allegations are raised through PubPeer and other public forums, the impact of Artificial Intelligence in identifying potential fabrication/falsification, to the Public Health Services’ proposed changes to the regulations, the rise of plagiarism-only allegations, and finally, how law enforcement has addressed these evolving concerns and renewed commitment to protecting the public from fabricated and/or falsified data in government-sponsored projects.